Parkinson-plus syndrome - Quiz
  • 1. What distinguishes Parkinson-plus syndromes from idiopathic Parkinson's disease?
A) Complete lack of tremor
B) Inability to walk
C) Additional clinical features
D) Age of onset exclusively under 30
  • 2. Which of the following is considered a Parkinson-plus syndrome?
A) Progressive supranuclear palsy
B) Amyotrophic lateral sclerosis
C) Multiple sclerosis
D) Huntington's disease
  • 3. How are Parkinson-plus syndromes classified based on pathology?
A) Primary and secondary
B) Synucleinopathies and tauopathies
C) Genetic and metabolic
D) Acute and chronic
  • 4. What is another name for the autonomic failure seen in multiple system atrophy?
A) Supranuclear gaze palsy
B) Pick's disease
C) Corticobasal degeneration
D) Shy–Drager syndrome
  • 5. Which of the following is a clinical feature distinguishing PPS from idiopathic PD?
A) Late-onset postural instability
B) Unilateral tremor
C) Symmetrical onset
D) Excellent response to levodopa
  • 6. What diagnostic tool uses 123I-iodobenzamide to assist in the differential diagnosis of PPS?
A) MRI
B) CT scan
C) SPECT
D) PET scan
  • 7. Which disorder is recognized as the second-most common type of neurodegenerative dementia?
A) Progressive supranuclear palsy
B) Pick's disease
C) Corticobasal degeneration
D) Dementia with Lewy bodies
  • 8. Olivopontocerebellar atrophy is characterized by which symptoms?
A) Ataxia and dysarthria
B) Alien limb and apraxia
C) Resting tremor and rigidity
D) Memory loss and hallucinations
  • 9. How do Parkinson-plus syndromes generally respond to antiparkinsonian medication compared to PD?
A) They are less likely to respond
B) They respond significantly better
C) They show identical response
D) They react negatively to all medication
  • 10. What is the primary approach to therapy for Parkinson-plus syndromes?
A) High-dose levodopa monotherapy
B) Preventative gene therapy
C) Multidisciplinary treatment of symptoms
D) Curative surgery
  • 11. Which of these is a recognized motor feature of Parkinson-plus syndromes?
A) Reduced axial muscle rigidity
B) Increased dopamine production
C) Supranuclear gaze palsy
D) Spontaneous recovery
  • 12. What is the nature of the progression of Parkinson-plus syndromes compared to PD?
A) Reversible
B) More slowly progressive
C) Stable without progression
D) More rapidly progressive
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