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Biopsy - Quiz
Contributed by: Burrows
  • 1. Who introduced the word 'biopsie' to the medical community in 1879?
A) Abulcasis
B) Marie Curie
C) Louis Pasteur
D) Ernest Besnier
  • 2. What does the Greek word 'bios' mean?
A) Death
B) Life
C) Tissue
D) Sight
  • 3. Which ancient physician developed one of the earliest diagnostic biopsies?
A) Avicenna
B) Abulcasis
C) Galen
D) Hippocrates
  • 4. What is an excisional biopsy?
A) Removal of a small cell cluster
B) A scan of the tumor site
C) A blood test for cancer
D) Removal of an entire lump or suspicious area
  • 5. What is examined in a biopsy specimen to see if the disease has spread beyond the biopsied area?
A) The entire organ
B) Surgical margin
C) Cell nucleus
D) Blood vessel density
  • 6. What does a 'positive margin' indicate in a biopsy?
A) The lesion is benign
B) The biopsy was unsuccessful
C) Disease was found at the edges
D) No further surgery is needed
  • 7. Which biopsy type does not preserve the histological architecture of the tissue cells?
A) Fine needle aspiration biopsy
B) Shave biopsy
C) Punch biopsy
D) Excisional biopsy
  • 8. What is the primary purpose of a liquid biopsy?
A) To surgically remove a tumor
B) To perform a deep tissue incision
C) To examine tissue structure under a microscope
D) To detect cancer cells or substances in body fluid
  • 9. What is a main advantage of cell-free circulating tumor DNA (cfDNA) assays over CTC assays?
A) They are cheaper to produce
B) They have zero risk of false negatives
C) They can diagnose the site of the tumor
D) There is approximately 100 times more cfDNA than DNA in circulating tumor cells
  • 10. Why are liquid biopsies considered an advantage over tissue biopsies regarding tumor genetics?
A) They allow for monitoring rapid, dynamic genetic changes
B) They require no specialized laboratory equipment
C) They provide a better look at tissue architecture
D) They are always 100% accurate
  • 11. What is a major drawback of liquid biopsies?
A) They are too painful for the patient
B) They cannot be used to diagnose cancer
C) They involve high radiation exposure
D) They require surgery
  • 12. What does 'pathologic staging' involve in a mastectomy specimen?
A) Revealing the extent of cancer spread
B) Checking for bacterial infection
C) Removing the skin surface
D) Testing the patient's blood type
  • 13. Which professionals can perform a biopsy?
A) Nurses
B) Laboratory technicians
C) Dentists
D) Medical students
  • 14. In the context of the text, what is a resection?
A) A blood test for tumor DNA
B) A biopsy that only takes a tiny fragment
C) A larger excisional specimen taken by a surgeon to eradicate a known lesion
D) A needle aspiration of fluid
  • 15. What do liquid biopsies analyze to track tumor progression?
A) Tissue density in the liver
B) Biopsy of bone marrow
C) Circulating tumor cells and cell-free DNA
D) X-ray images of the lungs
  • 16. Which artery is frequently biopsied when vasculitis is suspected?
A) Radial artery
B) Carotid artery
C) Femoral artery
D) Temporal artery
  • 17. What is vital in the diagnosis of Crescentic glomerulonephritis?
A) Genetic sequencing
B) Immunofluorescence
C) MRI imaging
D) Blood glucose testing
  • 18. Which condition involves the accumulation of degraded proteins in body tissues?
A) Crohn's disease
B) Vasculitis
C) Glomerulonephritis
D) Amyloidosis
  • 19. Where is a biopsy commonly taken to diagnose amyloidosis?
A) Heart
B) Brain
C) Gingiva
D) Liver
  • 20. Who specializes in diagnosing diseases by examining tissue under a microscope?
A) Radiologist
B) General practitioner
C) Surgeon
D) Pathologist
  • 21. What is done to the biopsy sample at the pathology laboratory to make individual cells more visible?
A) Stained with dyes
B) Frozen at extreme temperatures
C) Dissolved in acid
D) Exposed to radiation
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