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Parkinson-plus syndrome - Quiz
Contributed by: Austin
  • 1. What distinguishes Parkinson-plus syndromes from idiopathic Parkinson's disease?
A) Inability to walk
B) Additional clinical features
C) Complete lack of tremor
D) Age of onset exclusively under 30
  • 2. Which of the following is considered a Parkinson-plus syndrome?
A) Amyotrophic lateral sclerosis
B) Huntington's disease
C) Progressive supranuclear palsy
D) Multiple sclerosis
  • 3. How are Parkinson-plus syndromes classified based on pathology?
A) Synucleinopathies and tauopathies
B) Acute and chronic
C) Genetic and metabolic
D) Primary and secondary
  • 4. What is another name for the autonomic failure seen in multiple system atrophy?
A) Supranuclear gaze palsy
B) Pick's disease
C) Shy–Drager syndrome
D) Corticobasal degeneration
  • 5. Which of the following is a clinical feature distinguishing PPS from idiopathic PD?
A) Symmetrical onset
B) Unilateral tremor
C) Excellent response to levodopa
D) Late-onset postural instability
  • 6. What diagnostic tool uses 123I-iodobenzamide to assist in the differential diagnosis of PPS?
A) SPECT
B) MRI
C) CT scan
D) PET scan
  • 7. Which disorder is recognized as the second-most common type of neurodegenerative dementia?
A) Corticobasal degeneration
B) Dementia with Lewy bodies
C) Pick's disease
D) Progressive supranuclear palsy
  • 8. Olivopontocerebellar atrophy is characterized by which symptoms?
A) Ataxia and dysarthria
B) Resting tremor and rigidity
C) Alien limb and apraxia
D) Memory loss and hallucinations
  • 9. How do Parkinson-plus syndromes generally respond to antiparkinsonian medication compared to PD?
A) They respond significantly better
B) They are less likely to respond
C) They show identical response
D) They react negatively to all medication
  • 10. What is the primary approach to therapy for Parkinson-plus syndromes?
A) Multidisciplinary treatment of symptoms
B) High-dose levodopa monotherapy
C) Curative surgery
D) Preventative gene therapy
  • 11. Which of these is a recognized motor feature of Parkinson-plus syndromes?
A) Supranuclear gaze palsy
B) Spontaneous recovery
C) Increased dopamine production
D) Reduced axial muscle rigidity
  • 12. What is the nature of the progression of Parkinson-plus syndromes compared to PD?
A) Stable without progression
B) More slowly progressive
C) More rapidly progressive
D) Reversible
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